Immunochemical and cytotoxic activities of Shigella dysenteriae 1 (shiga) and shiga-like toxins.

نویسندگان

  • A D O'Brien
  • G D Laveck
چکیده

Toxins in culture supernatants and bacterial lysates of S. dysenteriae 1 and S. flexneri were quantitated by a cytotoxicity assay and a newly developed radioimmunoassay. Cytotoxin titers paralleled toxin antigen levels. Thus, variations in cytotoxicity among shigellae probably reflect differences in toxin yield rather than specific activity (cytotoxicity per microgram of toxin antigen).

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عنوان ژورنال:
  • Infection and immunity

دوره 35 3  شماره 

صفحات  -

تاریخ انتشار 1982